Sodium orthovanadate ( —— )

产品货号. M11533 CAS No. 13721-39-6

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Sodium orthovanadate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Sodium orthovanadate is a commonly used general inhibitor for PTP (protein tyrosine phosphatases), alkaline phosphatase (ALP) and ATPase.
产品描述

Sodium orthovanadate is a commonly used general inhibitor for PTP (protein tyrosine phosphatases), alkaline phosphatase (ALP) and ATPase. Na3VO4 acts as a competitive inhibitor and is completely reversible upon the addition of EDTA or by dilution. The PTP activities are conveniently separable from the protein phosphoseryl and phosphothreonyl phosphatase (PSP) activities inhibited by Fluoride and EDTA. Vanadate is routinely used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays. Sodium Orthovanadate is an inhibitor of AK and PFK.
同义词

——
通路

Endocrinology/Hormones
靶点

ATPase
受体

(Na,K)-ATPase; Phosphatase
研究领域

Other Indications
适应症

——

1.Wu Y, et al. Acta Pharmacol Sin, 2005, 26(3), 345-352.
2. Cantley LC Jr, et al. J Biol Chem, 1977, 252(21), 7421-7423.

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